How and Why Macrophages are Connected with the Parkinson’s Disease: A Short Review to Develop a Therapeutic Strategy for PD

نویسندگان

چکیده

Chronic neuro-inflammation cause the neural cell death including dopaminergic cells and ultimate results Parkinson’s disease (PD). In an MPTP-induced PD animal model increased peripheral pro-inflammatory M1 macrophages (M1- MFs) were found. Polarization of this M1-type MFs to anti-inflammatory M2-type revealed a potential therapeutic benefit for patients. Here we highlight concept re-education as method therapies, how can deploy our knowledge find out regimen treatment.

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ژورنال

عنوان ژورنال: Biomedical research and clinical reviews

سال: 2022

ISSN: ['2692-9406']

DOI: https://doi.org/10.31579/2692-9406/127